Mind your heart: the epigenetic consequences of heart failure on brain function
نویسندگان
چکیده
منابع مشابه
Mind your heart.
Clinicians as far back as the father of internal medicine, Sir William Osler, have noted characteristic behavioral patterns in patients with heart disease. In 1897, Osler observed that “the typical heart disease patient is a keen and ambitious man . . . whose engine is always at full speed ahead” (1). Almost a century later, cardiologists Friedman and Rosenman picked up on this theme by linking...
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Tissue inhibitor of matrix metalloprotease 4 (TIMP4) is endogenously one of the key modulators of matrix metalloprotease 9 (MMP9) and we have reported earlier that cardiac specific TIMP4 instigates contractility and helps in differentiation of cardiac progenitor cells. Although studies show that the expression of TIMP4 goes down in heart failure but the mechanism is unknown. This study aims to ...
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ژورنال
عنوان ژورنال: EMBO Molecular Medicine
سال: 2021
ISSN: 1757-4676,1757-4684
DOI: 10.15252/emmm.202013785